Two goals from returning hero Cristiano Ronaldo sent Manchester United joint top of the Premier League after early season pace-setters Tottenham Hotspur fell to a surprise 3-0 loss at Crystal Palace.
Champions Manchester City made it three wins out of four with a 1-0 win at Leicester City while Arsenal got their first victory of the campaign, with Pierre-Emerick Aubameyang on target in a 1-0 win over Norwich City.
Manchester United and Chelsea lead on 10 points with an identical goal difference after four games with Manchester City a point behind along with Brighton & Hove Albion, who won 1-0 at promoted Brentford, and Spurs.
Chelsea beat Aston Villa 3-0 in the late game to register their 600th victory in the Premier League.
Romelu Lukaku and Mateo Kovacic finally opened their accounts at Stamford Bridge, with the Belgian striker scoring twice, while goalkeeper Edouard Mendy denied Villa numerous times to keep his third clean sheet.
Ronaldo’s return to United from Juventus last month brought with it the promise of excitement and goals at Old Trafford and his second debut certainly lived up to the billing.
The 36-year-old fired his side ahead just before the break, pouncing to slot home from close range after Newcastle keeper Freddie Woodman was unable to hold on to a low drive from Mason Greenwood.
After Javier Manquillo brought Newcastle level following the break, Ronaldo produced a trademark strike. He burst into the box as he collected a through ball from Luke Shaw before drilling it through the legs of Woodman.